Science

At iove, we bring rigorous lab science to your daily life. We create solutions based on real, proven biology so you can trust our scientifically-backed products.

Science iove

We are not just another brand

iove is not born from a trend or an opportunistic formulation.
It is born from years of biomedical research, collaboration with internationally recognized scientific groups, and an approach that understands longevity and cellular health from its pathophysiological basis.
Our difference is not in promising quick results, but in working on the same biological mechanisms that science studies in contexts of maximum clinical demand.

To the Origin

How it works

Aging begins in the cell.
Oxidative stress and ROS (reactive oxygen species) damage cells and disrupt their functioning.

Pteroyouth®

Activator of "longevity-regulating" proteins

It activates SIRT1 and SIRT3, proteins that help repair DNA, reduce inflammation, and promote energy production.

NAD⁺

Pteroyouth® formulation increases NAD+ levels

NAD⁺ is a molecule cells need to produce energy and activate sirtuins. Its concentration naturally decreases with age.

Nrf2

Enhances cell defense and helps balance inflammation.

It strengthens cellular antioxidant defenses and helps modulate inflammatory processes associated with oxidative stress.
Pteroyouth® supports the activation of the Nrf2 pathway, promoting an endogenous antioxidant response and contributing to a cellular environment that limits NF-κB dependent inflammatory activation.

Cell regeneration

Pteroyouth® promotes strong, healthy cells.

Pteroyouth® supports natural cell renewal mechanisms, promoting autophagy and mitophagy, key processes for eliminating damaged components and dysfunctional mitochondria, maintaining energy efficiency, and preserving long-term cellular health.

Real Cell Protection

Proven cellular resilience.

Unlike other supplements, Pteroyouth® has demonstrated functional cellular protection in real high-stress situations, supporting the body's ability to adapt and recover.
Its formula reduces oxidative damage, supports DNA repair, and promotes cellular resilience by activating Nrf2, modulating NF‑κB, inhibiting cell death, and inducing autophagy and mitophagy, key processes for cellular recovery and balance.

Real, Not Superficial, Research

iove's scientific core has been developed in collaboration with top-tier academic and hospital institutions, including:

University of Valencia

Hospital Universitari i Politècnic La Fe (Valencia)

University of Barcelona

University of the Balearic Islands

These alliances are neither consultative nor superficial. They are active collaborations in preclinical and translational research, with results published in peer-reviewed international scientific journals.

From oncology and radiation protection to the study of longevity

One of the differentiating elements of the iove approach is the origin of the knowledge that gives rise to Pteroyouth®.

The active ingredients and cellular pathways on which Pteroyouth® acts have been initially studied in oncology and radioprotection models, contexts where:

cellular damage is extreme,

oxidative stress is massive,

inflammation is systemic,

and DNA repair and mitochondrial recovery capacity determine survival.

From a pathophysiological point of view, these processes are the same as those underlying aging and loss of cellular resilience, although in this case chronically and progressively. Therefore, research in ionizing radiation and oncology constitutes an accelerated and extremely demanding model to study the key mechanisms of longevity.

Radioprotection studies supporting the iove approach

Various studies carried out in collaboration with the University of Valencia and La Fe Hospital have investigated combinations of polyphenols, NAD⁺ precursors, and cell modulators in models exposed to ionizing radiation.
These studies have demonstrated, among other things:

  • significant reduction of oxidative damage to DNA, proteins, and lipids,
  • activation of the Nrf2 pathway and strengthening of endogenous antioxidant defenses,
  • modulation of inflammation through NF-κB,
  • activation of the SIRT1 / SIRT3 – PGC-1α axis, key for mitochondrial function,
  • improvement of PARP1-dependent DNA repair mechanisms,
  • preservation of cell viability in highly sensitive tissues.

These same mechanisms are what we now know determine the speed and quality of the aging process. Pteroyouth® arises precisely from the integration of these findings into a platform applicable to both the skin and the body as a whole.

The same scientific core for cosmetics and food supplements

Most brands separate cosmetic discourse from nutritional discourse.
At iove, both stem from the same scientific core.
Pteroyouth® is not an added ingredient; it is a common biological platform that allows intervention in the same cellular pathways through two complementary routes:

  • Advanced cosmetics, acting locally on cutaneous cellular function.
  • Nutritional support, accompanying these same processes at a systemic level.

This ensures biological coherence, continuity over time, and an approach that respects the body's actual physiology.

Accessible and Transparent Science

We believe the science behind a product should be verifiable, not a slogan.
That's why iove provides the following for those who want to delve deeper:

  • published scientific articles,
  • verifiable academic collaborations, and
  • an evidence-based approach, not one based on promises.

Beauty, well-being, and longevity are not isolated concepts. They are the consequence of how our cells function when properly supported.

iove
Where science is not simplified.
It's translated.